Ulfa, Madu Pratiwi (2018) EFEK ANTIHIPERTENSI EKSTRAK ETANOL UMBI WORTEL (Daucus carota L.) PADA TIKUS HIPERTENSI YANG DIINDUKSI MONOSODIUM GLUTAMAT (MSG). Skripsi thesis, Universitas Wahid Hasyim Semarang.
|
Text
COVER SAMPAI DAFTAR ISI.pdf Download (413kB) | Preview |
|
|
Text
BAB I.pdf Download (345kB) | Preview |
|
Text
BAB II.pdf Restricted to Registered users only Download (548kB) |
||
Text
BAB III.pdf Restricted to Registered users only Download (279kB) |
||
Text
BAB IV.pdf Restricted to Registered users only Download (127kB) |
||
|
Text
LAMPIRAN PDF.pdf Download (1MB) | Preview |
|
|
Text
DAFTAR PUSTAKA PDF.pdf Download (279kB) | Preview |
Abstract
The previous studies reported that carrot juice had an antihypertensive effect. This study aims to prove the antihypertensives effects of carrot tuber ethanol extract (CTEE) in MSG-induced hypertensive rats and to set the pattern of its antihypertensive effect based on dose. This study used randomized pre-test and post-test matched control group design. CTEE was prepared by using maceration method with ethanol solvent 70%. The hypertension rats induced with MSG 100 mg/kg BW/day for 14 days. The 25 hypertension rats were grouped into five treatment groups, hypertension control (CMC-Na 0,5% 12,5 mL/kg BW/day), positive control (furosemide 5,04 mg/kg BW), and CTEE (100 ; 200 and 400) mg/kg BW. The extracts were given once a day for 14 days orally. The systolic and diastolic blood pressure of hypertensive rats before and after treatment statistically analyzed by Wilcoxon test or T paired, while the blood pressure decrease of hypertensive rats that got treated with CTEE was analyzed by one way ANOVA test. The results showed that CTEE (100, 200 and 400) mg/kg BW/day for 14 days had antihypertensive effect on MSG-induced hypertensive rats. However, the antihypertensive effect of CTEE does not follow a dose-dependent pattern in both systolic and diastolic blood pressure.
Item Type: | Thesis (Skripsi) |
---|---|
Subjects: | R Medicine > RM Therapeutics. Pharmacology |
Divisions: | Fakultas Farmasi > Program Studi Farmasi |
Depositing User: | eprints perpustakaan unwahas |
Date Deposited: | 10 Aug 2018 04:17 |
Last Modified: | 10 Aug 2018 04:17 |
URI: | http://eprints.unwahas.ac.id/id/eprint/1034 |
Actions (login required)
View Item |