Sri, Handayani (2018) POTENSI EKSTRAK ETANOL RIMPANG KENCUR (Kaempferia galanga L.) SEBAGAI PENURUN KADAR KOLESTEROL TOTAL DAN TRIGLISERIDA TIKUS BETINA GALUR WISTAR TEROVARIEKTOMI. Skripsi thesis, Universitas Wahid Hasyim Semarang.
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Abstract
Hipercholesterolemia is one of the effects caused by the decline in estrogen at menopause. Rhizome Kaempferia galanga contains flavonoids alleged phytoestrogen compounds. The purpose of this study was to determine the rhizome Kaempferia galanga L estrogenic effect on levels of total cholesterol and triglyceride levels in female rats Wistar terovariektomi. This study is an experimental research using only posttest controlled group design. Wistar female rats as many as 30 individuals were placed in plastic cages with pedestal chaff and fed in the form of pellets and given a drink of water taps are each provided ad libitum. Extracts are given in the form of a suspension in the solvent 0.5% CMC-Na. Extract solution made just before it was given to test animals. Rats were divided into six treatment groups with 5 rats each group are: Group I base line non-ovariectomy, Group II base line ovariectomy, Group III treatment of 0.5% CMC-Na (negative control), Group IV treatment estradiol 2 mg day (control positif), Group V extract treatment dose of 500 mg/kg, Group VI extract treatment dose of 1000 mg/kg. Treatment of rat blood serum taken through orbitalis sinus using the method CHOD-PAP and GPO-PAP. Data were analyzed by One Way ANOVA followed by Tukey test. The results showed that the ethanol extract of rhizome Kaempferia galanga L 1000 mg/KgBBcan be lower total cholesterol with significant results(p≤0,005).Howeever, it is not capable of lowering blood trigliseride in female rats.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Farmasi > Program Studi Farmasi |
| Depositing User: | eprints perpustakaan unwahas |
| Date Deposited: | 10 Aug 2018 04:02 |
| Last Modified: | 10 Aug 2018 04:02 |
| URI: | http://eprints.unwahas.ac.id/id/eprint/1027 |
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